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Kawasaki Disease
(mucocutaneous lymph node syndrome)

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Affecting children under the age of 5, diagnostic criteria include at least 5 days of fever, conjunctival injection without exudate, red-fissured lips, strawberry tongue, erythematous rash, redness and/or edema of palms and soles, and cervical adenopathy.

Although generally benign and self-limited, it is associated with coronary artery aneurisms in about 25% of affected children. Early treatment with high-dose IV gamma-globulin and oral aspirin have been shown to reduce the incidence of aneurisms.

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